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Braz. j. med. biol. res ; 24(4): 421-4, 1991. tab
Artigo em Inglês | LILACS | ID: lil-99472

RESUMO

The effects of an aqueous extract of guaraná (Paullinia cupana) on rabbit platelet aggregation and thromboxane synthesis were examined. The guaraná extract (100 mg/ml) and fractions separated by TLC (origin and xanthines) decreased platelet aggregation (37.27 and 31% of control values, respectively) and platelet thromboxane formation from [14C]-arachidonic acid (78, 70 and 50% of control values respectively). The decreased thromboxane synthesis could be responsible, at least in part, for the antiaggregatory action of guaraná


Assuntos
Animais , Coelhos , Extratos Vegetais/farmacologia , Plantas Medicinais , Inibidores da Agregação Plaquetária , Tromboxanos/biossíntese , Agregação Plaquetária
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